Polpharma Biologics is part of the Polpharma Group, one of the largest pharmaceutical companies in Central and Eastern Europe. We focus on the development and production of biological medicines. Our international team consist of experiences experts and young scientists. We share common goal - to improve the quality of patients' ;ife with more availabe biological medicines of the hishest quality.
Downstream Process Development Specialist
Location: Gdańsk
If you want to work:
- in one of the most modern biotechnology centres in Europe
- in a place where professionals from all over the world work on the highest-quality equipment
- in the production of biotechnological drugs, which give access to effective therapy to more patiens
- in a company that will give you stable employment, competitive renumerations, attractive benefits and the opportunity to participate in trainings at home and abroad
Currently we’re looking for
1
Downstream Process Development Specialist
Join “start-up” Biologics division with strong international and local team at site!
We are waiting just for you!
What will you do?
- Downstream process development, optimization, characterization, and technology transfer
- Planning and execution of laboratory scale studies for development and optimization of protein purification steps, including chromatography, filtration and membrane separations
- Document observations, analyzing data, reporting results and conclusions for each experimental study
- Trouble shooting activities and deviation assessment
- Assessing improvement in DSP setup
- Optimization of the process with regards of technical as well economic aspects
- Evaluation of external suppliers of resins, filter membranes, disposable materials etc.
- Supporting GMP manufacturing through process investigations and during process transfer
- Design and execution of experiments based on DoE approach
- Collaboration with USP, Analytical and Pilot Plant departments in order to achieve optimal results
- Supporting and coordinating work of junior team members in their assigned tasks
What do we expect?
- MS or PhD in Biotechnology or related disciplines
- 2+ years of experience in purification process development (preferably antibodies) in industry is highly desirable, however the candidates with strong experience and demonstrated track record in development and optimization of protein purifications in academia will also be considered. Experience with TFF and normal-flow filtration is a plus
- A strong understanding of protein chromatography
- Proven ability to work independently in hands-on laboratory setting
- Experience in handling of lab scale chromatography systems (such as ÄKTA systems) is required. Experience with filtration units is a plus
- Analytical skills with knowledge of spectrophotometric methods is desired
- Experience writing technical development or scientific reports/publications
- Basic knowledge of GMP standards is a plus
- Fluent English
Poznaj
POLPHARMA S.A.
Zdrowe jutro zaczyna się od ludzi, którzy tworzą Polpharmę – od ich wiedzy, zaangażowania i pasji. Wspólnie dbamy o zdrowie innych i tworzymy środowisko, w którym każdy może być sobą. Rozwijamy się w zgodzie z własnymi ambicjami, niezależnie od obszaru, w jakim działamy. Razem z nami możesz realnie wpływać na zdrowie i dobrostan innych.